Understanding OrthoBiologics
General Overview Articles
- OrthoBiologics Overview
- Is Biologic Treatment Right For You?
- Biologics at Midwest Orthopaedics at Rush
- Biologic Research Impacting Patient Care
- Navigating the Field of OrthoBiologics
- ACP Patient Guide
- Angel Patient Guide
- BMAC at Midwest Orthopaedics at Rush
- The Use of Fat to Augment Healing (Lipogem Procedure)
- What is Lipogem?
- ISCT Position Paper: Key Considerations to support evidence-based cell and gene therapies and oppose marketing of unproven products
General Overview Videos
- Innovations in OrthoBiologics
- Blood-derived Products: Hype or Fake?
- Indications and Expectations Related to the Use of OrthoBiologics
- New Frontiers in Biologics
- ON Foundation Live Q&A Series: Perspectives on Orthoregeneration with Dr. Brian Cole
- OrthoBiologic Efforts at Rush
- Biologic Association Presentation: Platelet Rich Plasma
- Biologic Association Presentation: The Business of PRP – In the Office & in the Operating Room
- PRP and Research at Rush
- Platelet Rich Plasma and Injection Technique
- Bone Marrow Aspiration from 2017 Chicago Sports Medicine Symposium
Research Articles: Knee
- A Prospective, Randomized, Double-Blind Clinical Trial to Investigate the Efficacy of Autologous Bone Marrow Aspirate Concentrate During Arthroscopic Meniscectomy in Patients With Early Knee Osteoarthritis (2024)
- ACL Reconstruction with Bone-Tendon-Bone Allografts Improved with BMAC Injection (2022)
- Anti-inflammatory and Matrix Restorative Mechanisms of PRP in Osteoarthritis: Response to Andia and Maffulli (2014)
- Anti-inflammatory and Matrix Restorative Mechanisms of PRP in Osteoarthritis: Response to Patel and Dhillon (2014)
- Biologic Cell Therapies (2019)
- Biologic Research Impacting Patient Care (2023)
- BMAC May Accelerate Allograft Ligamentization in ACL Reconstructions (2022)
- Bone Marrow Aspirate and Its Use on Enhancing Allograft Intergration (2017)
- Cartilage Restoration: Allogeneic Cartilage, PRP, and Autologous Cartilage Sealed With Activated Autologous Serum (2020)
- Coding and Reimbursement Issues for PRP (2011)
- Consensus Statement on the Use of OrthoBiologics (2018)
- Considerations for the Use of PRP in Orthopedics (2014)
- Cord Blood–Derived Mesenchymal Stem Cell Implantation for Cartilage Defects (2021)
- Editorial Commentary on Orthobiologic Use During Cartilage Restoration (2020)
- Effect of Leukocyte Concentration in PRP for OA Treatment (2016)
- Effects of PRP on Cartilage (2011)
- Emerging Biologics in Orthopedics Editorial (2015)
- Emerging Technologies in Cartilage Restoration (2018)
- Evidence Based Recommendations for PRP Use (2018)
- Growth Factors & Bone Repair (1999)
- HA vs PRP in the Management of Knee OA (2016)
- Improving Injection Accuracy of the Shoulder, Elbow and Knee (2011)
- Injection Options for Knee Osteoarthritis (2018)
- Nonoperative and Operative Soft-Tissue and Cartilage Regeneration and Orthopaedic Biologics of the Knee: An Orthoregeneration Network (ON) Foundation Review (2021)
- Novel Injection Therapy for Advanced Osteoarthritis of the Knee (2017)
- Orthobiologics for Cartilage Defects of the Knee (2019)
- Orthobiologics for Osteoarthritis (2018)
- Overview of Amniotic Tissue in Regenerative Medicine (2016)
- Overview of PRP in Orthopedics in 2017
- Pirfenidone Reduces Subchondral Bone Loss and Fibrosis after Mouse Cartilage Injury (2018)
- PRP and Cartilage Repair (2013)
- PRP and Cartilage: Review of Basic Science (2013)
- PRP and Growth Factor and Cellular Composition (2011)
- PRP for Treatment of Knee Osteoarthritis (2020)
- PRP in Cartilage Repair and Arthritis (2015)
- PRP: What It Is and What It Does (2012)
- PRP: Where Are We Now and Where are We Going? (2010)
- Regenerative Potential of MSCs for Treatment of Knee OA and Chondral Defects (2020)
- Response of Cartilage Cells to Growth Factors (2008)
- Rogue Stem Cell Clinics (2020)
- Role of Growth Factors in Cartilage Repair (2011)
- Role of PRP in Articular Cartilage Injury and Disease (2014)
- Role of PRP in Osteoarthritis (2014)
- Role of Stem Cells in Osteoarthritis (2014)
- Safety and Efficacy of Postoperative Nonsteroidal Anti-inflammatory Drugs in Sports Medicine (2022)
- The 2020 NBA Orthobiologics Consensus Statement
- The Effects of Knee Position on XR Findings and Response to Biologic Treatment (2017)
- The Placebo Effect in Injection Therapy (2016)
- The Role of Orthobiologics in the Management of Cartilage and Meniscal Injuries in Sports (2020)
- The Role of Orthobiologics in the Management of Ligament and Muscle Injuries in Sports (2020)
- The Role of Orthobiologics in the Management of Tendon and Fascia Injuries in Sports (2020)
- The Role of Platelet Rich Plasma in the Treatment of Cartilage Disease (2019)
- The Use of PRP and Hyaluronic Acid for Osteoarthritis (2020)
- The utility of Biologics and Cartilage Transplantation Techniques (2018)
- Treatment of OCD with Subchondral Injection of Calcium Phosphate (2013)
- Use of Biologics for Osteoarthritis (2020)
- Use of Bone Marrow Concentrate Improves Osteochondral Allograft Integration (2017)
- Use of Corticosteroids after Knee Arthroscopy: Randomized Controlled Trial (2009)
- Use of HA and PRP for Arthritis: Letter to the Editor (2013)
- Use of PRP in Osteoarthritis (2018)
Videos and Presentations: Knee
- Biologic Association Presentation: Clinical Application of OrthoBiologics – Tendons
- Dr. Cole Discusses PRP and HA for the Treatment of Osteoarthritis
- Dr. Cole Lectures on the Use of MSCs to Treat Osteoarthritis
- Dr. Cole’s Presentation On the Use of Injections to Manage Osteoarthritis
- Podcast on the role of PRP and HA in the treatment of osteoarthritis (2016)
- Stem Cells for the Treatment of Arthritis
- The Use of OrthoBiologics in Clinical Practice (2022)
Research Articles: Shoulder
- Augmentation of Rotator Cuff Healing with Bipolar Radiofrequency (2007)
- Biologic Cell Therapies (2019)
- Biologics in shoulder and elbow pathology (2020)
- Biologic Research Impacting Patient Care (2023)
- BMAC Augmentation May Produce a Structurally Superior Rotator Cuff Repair (2023)
- Clinical Outcomes Following Superior Capsular Reconstruction with Dermal Allograft (2021)
- Coding and Reimbursement Issues for PRP (2011)
- Consensus Statement on the Use of OrthoBiologics (2018)
- Considerations for the Use of PRP in Orthopedics (2014)
- Emerging Biologics in Orthopedics Editorial (2015)
- Evidence Based Recommendations for PRP Use (2018)
- Growth Factors & Bone Repair (1999)
- Improving Injection Accuracy of the Shoulder, Elbow and Knee (2011)
- Nonoperative and Operative Soft-Tissue, Cartilage, and Bony Regeneration and Orthopaedic Biologics of the Shoulder: An Orthoregeneration Network (ON) Foundation Review (2021)
- Outcomes following rotator cuff repair with a patch (2016)
- Overview of PRP in Orthopedics (2017)
- Patch Augmentation and Extension for Complex Rotator Cuff Tears (2018)
- Promising Outcomes of Graft Augmentation for RCR (2022)
- PRP and Cartilage: Review of Basic Science (2013)
- PRP and Growth Factor and Cellular Composition (2011)
- PRP and Rotator Cuff Repair Outcomes (2016)
- PRP: What It Is and What It Does (2012)
- PRP: Where Are We Now and Where are We Going? (2010)
- RCR Augmentation with Patches (2006)
- RCR with Synthetic Patch Augmentation (2011)
- Role of PRP in Articular Cartilage Injury and Disease (2014)
- Rotator Cuff Augmentation with a Dermal Allograft to Improve Clinical Outcomes (2022)
- Safety and Efficacy of Postoperative Nonsteroidal Anti-inflammatory Drugs in Sports Medicine (2022)
- Surgical Technique – Rotator Cuff Repair with Patch Augmentation (2021)
- The 2020 NBA Orthobiologics Consensus Statement
- The Benefits of PRP in Culture for Rotator Cuff Tears (2015)
- Update on Superior Capsular Reconstruction (2020)
- Use of HA and PRP for Arthritis: Letter to the Editor (2013)
- Use of PRP and BMAC in Rotator Cuff Surgery (2017)
- Use of Stem Cells to Enhance Rotator Cuff Repair Outcomes (2014)
Videos and Presentations: Shoulder
- Biologic Association Presentation: Clinical Application of OrthoBiologics – RCR Augmentation
- Biologic Association Presentation: Clinical Application of OrthoBiologics – Tendons
- Biologic Augmentation of Rotator Cuff Tears
- Clinical Application of OrthoBiologics: RCR Augmentation
- Dr. Cole Discusses PRP and HA for the Treatment of Osteoarthritis
- Dr. Cole Lectures on the Use of Biologics to Improve Rotator Cuff Repair
- Dr. Cole Lectures on the Use of MSCs to Treat Osteoarthritis
- Dr. Cole’s Presentation On the Use of Injections to Manage Osteoarthritis
- Dr. Cole’s Use of Biologics During Rotator Cuff Repair
- Dr. Cole’s presentation on the use of injections to manage osteoarthritis (2018)
- OrthoBiologics as an Adjunct to Rotator Cuff Repair
- Stem Cells for the Treatment of Arthritis
- The Use of OrthoBiologics in Clinical Practice
- Use of PRP for Lateral Epicondylitis