Understanding OrthoBiologics
OrthoBiologics are natural substances such as cells, tissue, blood components, and growth factors that are harnessed to aid in the treatment of orthopedic conditions, such as osteoarthritis or ligament and tendon injuries. They may be used to replace lost tissue, stimulate regeneration and healing, reduce pain and inflammation and improve joint function, and can be administered as an office-based treatment, in the form of an injection, or at the time of surgery.
While research is ongoing, OrthoBiologics have been found to improve symptoms and surgical outcomes in clinical trials and practice, as they function like “biologic pharmacies,” delivering nutrients, growth factors, and various biologic molecules to a site of degeneration, injury or surgical repair. It is important to understand that OrthoBiologics are not necessarily related to stem cells, nor are they regenerative in nature. Research indicates it is the growth factors, and not the cells themselves, that impact inflammation and healing. For more information, view our Understanding OrthoBiologics brochure.
Types of OrthoBiologics
Platelet Rich Plasma (PRP)
PRP is obtained from the patient’s blood after it has been processed to concentrate platelets and certain white blood cells that enhance healing and reduce inflammation. PRP may be injected directly into the damaged tissue during an outpatient procedure, at the time of or following repair surgery. PRP does not increase surgical time, prolong recovery, or require extra sutures.
Bone Marrow Aspiration Concentrate (BMAC)
BMAC is obtained intra-operatively, while under anesthesia, from bone marrow that is removed from a bone region. BMAC is rich in cells, which produce proteins and growth factors necessary for healing and reducing inflammation. It does not increase surgical time, prolong recovery, or require extra sutures.
Adipose Tissue
Adipose tissue, or fat cells, have remarkable healing and regenerative properties. They are typically obtained from your waist, processed to remove impurities and inflammatory components, and then injected at the site of injury.
Learn more about Adipose Tissue
Frequently Asked Questions
View additional research articles and videos about orthobiologics